Roles of Presynaptic NMDA Receptors in Neurotransmission and Plasticity

被引：93

作者：

Banerjee, Abhishek ^{[1
,6
]}

Larsen, Rylan S. ^{[2
]}

Philpot, Benjamin D. ^{[3
,4
]}

Paulsen, Ole ^{[5
]}

机构：

[1] MIT, Dept Brain & Cognit Sci, E25-618, Cambridge, MA 02139 USA

[2] Allen Inst Brain Sci, Seattle, WA USA

[3] Univ N Carolina, Dept Cell Biol & Anat, Ctr Neurosci, Chapel Hill, NC USA

[4] Univ N Carolina, Carolina Inst Dev Disabil, Chapel Hill, NC USA

[5] Univ Cambridge, Dept Physiol Dev & Neurosci, Cambridge, England

[6] Univ Zurich, Brain Res Inst, Zurich, Switzerland

来源：

TRENDS IN NEUROSCIENCES | 2016年 / 39卷 / 01期

基金：

英国医学研究理事会; 英国生物技术与生命科学研究理事会; 美国国家卫生研究院;

关键词：

CEREBELLAR PURKINJE-CELLS; GLYCINE BINDING-SITES; GLUTAMATE RELEASE; SYNAPTIC PLASTICITY; TONIC FACILITATION; DEPENDENT PLASTICITY; PYRAMIDAL CELLS; EXPRESSION; MECHANISMS; DEPRESSION;

D O I：

10.1016/j.tins.2015.11.001

中图分类号：

Q189 [神经科学];

学科分类号：

071006 [神经生物学];

摘要：

Presynaptic NMDA receptors (preNMDARs) play pivotal roles in excitatory neurotransmission and synaptic plasticity. They facilitate presynaptic neurotransmitter release and modulate mechanisms controlling synaptic maturation and plasticity during formative periods of brain development. There is an increasing understanding of the roles of preNMDARs in experience-dependent synaptic and circuit-specific computation. In this review we summarize the latest understanding of compartment-specific expression and function of preNMDARs, and how they contribute to synapse-specific and circuit-level information processing.

引用

页码：26 / 39

页数：14

共 111 条

[1]

Ketamine and Rapid-Acting Antidepressants: A Window into a New Neurobiology for Mood Disorder Therapeutics [J].

Abdallah, Chadi G. ;

Sanacora, Gerard ;

Duman, Ronald S. ;

Krystal, John H. .

ANNUAL REVIEW OF MEDICINE, VOL 66, 2015, 66 :509-523

[2]

Distinct mechanisms of spike timing-dependent LTD at vertical and horizontal inputs onto L2/3 pyramidal neurons in mouse barrel cortex [J].

Banerjee, Abhishek ;

Gonzalez-Rueda, Ana ;

Sampaio-Baptista, Cassandra ;

Paulsen, Ole ;

Rodriguez-Moreno, Antonio .

PHYSIOLOGICAL REPORTS, 2014, 2 (03)

[3]

Double Dissociation of Spike Timing-Dependent Potentiation and Depression by Subunit-Preferring NMDA Receptor Antagonists in Mouse Barrel Cortex [J].

Banerjee, Abhishek ;

Meredith, Rhiannon M. ;

Rodriguez-Moreno, Antonio ;

Mierau, Susanna B. ;

Auberson, Yves P. ;

Paulsen, Ole .

CEREBRAL CORTEX, 2009, 19 (12) :2959-2969

[4]

Two coincidence detectors for spike timing-dependent plasticity in somatosensory cortex [J].

Bender, VA ;

Bender, KJ ;

Brasier, DJ ;

Feldman, DE .

JOURNAL OF NEUROSCIENCE, 2006, 26 (16) :4166-4177

[5]

Cell Selective Conditional Null Mutations of Serine Racemase Demonstrate a Predominate Localization in Cortical Glutamatergic Neurons [J].

Benneyworth, Michael A. ;

Li, Yan ;

Basu, Alo C. ;

Bolshakov, Vadim Y. ;

Coyle, Joseph T. .

CELLULAR AND MOLECULAR NEUROBIOLOGY, 2012, 32 (04) :613-624

[6]

Tonic facilitation of glutamate release by presynaptic N-methyl-D-aspartate autoreceptors in the entorhinal cortex [J].

Berretta, N ;

Jones, RSG .

NEUROSCIENCE, 1996, 75 (02) :339-344

[7]

Bidoret Celine, 2015, Front Synaptic Neurosci, V7, P1, DOI 10.3389/fnsyn.2015.00001

[8]

Presynaptic NR2A-containing NMDA receptors implement a high-pass filter synaptic plasticity rule [J].

Bidoret, Celine ;

Ayon, Annick ;

Barbour, Boris ;

Casado, Mariano .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2009, 106 (33) :14126-14131

[9]

LONG-LASTING POTENTIATION OF SYNAPTIC TRANSMISSION IN DENTATE AREA OF ANESTHETIZED RABBIT FOLLOWING STIMULATION OF PERFORANT PATH [J].

BLISS, TVP ;

LOMO, T .

JOURNAL OF PHYSIOLOGY-LONDON, 1973, 232 (02) :331-356

[10]

Endocannabinoid signaling in rat somatosensory cortex:: Laminar differences and involvement of specific interneuron types [J].

Bodor, AL ;

Katona, I ;

Nyíri, G ;

Mackie, K ;

Ledent, C ;

Hájos, N ;

Freund, TF .

JOURNAL OF NEUROSCIENCE, 2005, 25 (29) :6845-6856

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