The science and practice of carcinogen identification and evaluation

被引：46

作者：

Cogliano, VJ ^{[1
]}

Baan, RA ^{[1
]}

Straif, K ^{[1
]}

Grosse, Y ^{[1
]}

Secretan, MB ^{[1
]}

El Ghissassi, F ^{[1
]}

Kleihues, P ^{[1
]}

机构：

[1] Int Agcy Res Canc, Carcinogen Identificat & Evaluat, F-69372 Lyon 08, France

来源：

ENVIRONMENTAL HEALTH PERSPECTIVES | 2004年 / 112卷 / 13期

关键词：

Carcinogen; Carcinogen identification; Conflict of interests; Hazard identification; IARC Monographs;

D O I：

10.1289/ehp.6950

中图分类号：

X [环境科学、安全科学];

学科分类号：

08 ; 0830 ;

摘要：

Several national and international health agencies have established programs with the aim of identifying agents and exposures that cause cancer in humans. Carcinogen identification is an activity grounded in the scientific evaluation of the results of human epidemiologic studies, long-term bioassays in experimental animals, and other data relevant to an evaluation of carcinogenicity and its mechanisms. In this commentary, after a brief discussion of the science basis common to the evaluation of carcinogens across different programs, we discuss in more detail the principles and procedures currently used by the IARC Monographs program.

引用

页码：1269 / 1274

页数：6

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