Intraocular melanoma linked to occupations and chemical exposures

被引：72

作者：

Holly, EA ^{[1
]}

Aston, DA ^{[1
]}

Ahn, DK ^{[1
]}

Smith, AH ^{[1
]}

机构：

[1] UNIV CALIF SAN FRANCISCO,SCH MED,DEPT EPIDEMIOL & BIOSTAT,SAN FRANCISCO,CA

来源：

EPIDEMIOLOGY | 1996年 / 7卷 / 01期

关键词：

uveal melanoma; case control studies; epidemiologic methods; occupational exposure; men;

D O I：

10.1097/00001648-199601000-00010

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

We conducted a case-control study in the western United States to determine the relation between occupations or chemical exposures and increased risk of uveal melanoma. Among men (221 patients, 447 controls), we found increased risks for occupational groups who had intense exposure to ultraviolet light [odds ratio (OR) = 3.0; 95% confidence interval (CI) = 1.2-7.8], welding exposure (OR = 2.2; 95% CI = 1.3-3.5), and asbestos exposure (OR = 2.4; 95% CI = 1.5-3.9 for most likely exposed). The highest odds ratio was for the small number of men (nine cases, three controls) who were chemists, chemical engineers, and chemical technicians (OR = 5.9; 95% CI = 1.6-22.7). Odds ratios also were elevated for exposures to antifreeze, formaldehyde, pesticides, and carbon tetrachloride, but these findings, based on recall of specific chemical exposures, are more subject to recall bias than the findings based on occupational groups.

引用

页码：55 / 61

页数：7

共 30 条

[1]

Ries L.A.G., Hankey B.F., Miller B.A., Hartman A.M., Edwards B.K., Cancer Statistics Review 1973-88, (1991)

[2]

Albert D.M., Puliafito C.A., Choroidal melanoma possible exposure to industrial toxins, N Engl J Med, 296, pp. 634-635, (1977)

[3]

Albert D.M., Puliafito C.A., Fulton A.B., Robinson N.L., Zakov Z.N., Dryja T.P., Smith A.B., Egan E., Leffingwell S.S., Increased incidence of choroidal malignant melanoma occurring in a single population of chemical workers, Am J Ophthalmol, 89, pp. 323-337, (1980)

[4]

Enterline P.E., Hattley J., Henderson V., Asbestos and cancer: A cohort followed up to death, Br J ind Med, 44, pp. 396-401, (1987)

[5]

Michaels D., Zoloth S., Asbestos disease in sheet metal workers: Proportional mortality update, Am J ind Med, 13, pp. 731-734, (1988)

[6]

Holman C.D.J., Armstrong B.K., Heenan P.J., Relationship of cutaneous malignant melanoma to individual sunlight-exposure habits, J Natl Cancer Inst, 76, pp. 403-414, (1986)

[7]

Holly E.A., Aston D.A., Char D.H., Kristiansen J.J., Ahn D.K., Uveal melanoma in relation to ultraviolet light exposure and host factors, Cancer Res, 50, pp. 5773-5777, (1990)

[8]

Holly E.A., Aston D.A., Ahn D.K., Kristiansen J.J., Char D.H., No excess prior cancer in patients with uveal melanoma, Ophthalmology, 98, pp. 608-611, (1991)

[9]

Holly E.A., Aston D.A., Ahn D.K., Kristiansen J.J., Char D.H., Uveal melanoma, hormonal, and reproductive factors in women, Cancer Res, 51, pp. 1370-1372, (1991)

[10]

Waksberg J., Sampling methods for random digit dialing, J Am Stat Assoc, 73, pp. 40-46, (1978)

← 1 2 3 →