The genomic RNA in Ty1 virus-like particles is dimeric

被引：37

作者：

Feng, YX

Moore, SP

Garfinkel, DJ

Rein, A

机构：

[1] NCI, Frederick Canc Res & Dev Ctr, HIV Drug Resistance Program, Frederick, MD 21702 USA

[2] NCI, Frederick Canc Res & Dev Ctr, Gene Regulat & Chromosome Biol Lab, Frederick, MD 21702 USA

来源：

JOURNAL OF VIROLOGY | 2000年 / 74卷 / 22期

关键词：

D O I：

10.1128/JVI.74.22.10819-10821.2000

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The yeast retrotransposon Ty1 resembles retroviruses in a number of important respects but also shows several fundamental differences from them. We now report that, as in retroviruses, the genomic RNA in Ty1 virus-like particles is dimeric. The Ty1 dimers also resemble retroviral dimers in that they are stabilized during the proteolytic maturation of the particle. The statbilization of the dimer suggests that one of the cleavage products of TyA1 possesses nucleic acid chaperone activity.

引用

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页码：10819 / 10821

页数：3

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