New dimensions in the pharmacologic treatment of schizophrenia and related psychoses

被引：25

作者：

Buckley, PF

机构：

[1] CASE WESTERN RESERVE UNIV,DEPT PSYCHIAT,CLEVELAND,OH 44106

[2] CASE WESTERN RESERVE UNIV,NORTHCOAST BEHAV HEALTHCARE SYST,CLEVELAND,OH 44106

来源：

JOURNAL OF CLINICAL PHARMACOLOGY | 1997年 / 37卷 / 05期

关键词：

D O I：

10.1002/j.1552-4604.1997.tb04314.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

During the past 5 years unprecedented advances have taken place in the psychopharmacology of schizophrenia and related psychoses. Clozapine and risperidone, two prototypic novel antipsychotic drugs, have had a significant impact on the treatment of psychotic disorders. Additionally, they have ushered in another generation of antipsychotic drugs with complex pharmacologic profiles, potentially enhanced efficacy, and more benign side-effect profiles than previously associated with conventional antipsychotic medications. This review highlights these developments, implications for the management of psychotic disorders, and the use of novel antipsychotic drugs in specific clinical subgroups.

引用

页码：363 / 378

页数：16

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