Palladium-catalyzed homocoupling of arylboronic acids and esters using fluoride in aqueous solvents

被引：65

作者：

Punna, S

Díaz, DD

Finn, MG

机构：

[1] Scripps Res Inst, Dept Chem, La Jolla, CA 92037 USA

[2] Scripps Res Inst, Skaggs Inst Chem Biol, La Jolla, CA 92037 USA

来源：

SYNLETT | 2004年 / 13期

关键词：

boronic acids; palladium; fluoride; biaryls; water;

D O I：

10.1055/s-2004-832845

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Homocoupling of both arylboronic acids and esters has been found to proceed using catalytic amounts of Pd-II and stoichiometric amounts of TBAF under air atmosphere at room temperature, offering a mild and efficient protocol for the synthesis of symmetrical biaryls via C(sp(2))-C(sp(2)) bond formation. Aryl boronic acids bearing bromide substitution form polyphenylenes.

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收藏

页码：2351 / 2354

页数：4

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