Nanoparticles: A personal experience for formulating poorly water soluble drugs

被引：75

作者：

Cooper, Eugene R.

机构：

[1] Berwyn PA 19312

来源：

JOURNAL OF CONTROLLED RELEASE | 2010年 / 141卷 / 03期

关键词：

Poorly soluble drugs; Particle size reduction; Enhanced bioavailability; Nanosizing;

D O I：

10.1016/j.jconrel.2009.10.006

中图分类号：

O6 [化学];

学科分类号：

070301 [无机化学];

摘要：

This short paper is a personal account of the development of techniques to enhance the bioavailability of a series of poorly soluble drugs by particle size reduction to the nanometer size range. This is a nanotechnological approach which has come of age and has had a practical impact on drug delivery. The drug is in effect the nanosystem. (C) 2009 Elsevier B.V. All rights reserved.

引用

页码：300 / 302

页数：3