Carbon nanotube array-based biosensor

被引:319
作者
Sotiropoulou, S [1 ]
Chaniotakis, NA [1 ]
机构
[1] Univ Crete, Dept Chem, Analyt Chem Lab, Iraklion 71409, Crete, Greece
关键词
carbon nanotube; biosensor; array; glucose oxidase;
D O I
10.1007/s00216-002-1617-z
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Aligned multi-wall carbon nanotubes (MWNT) grown on platinum substrate are used for the development of an amperometric biosensor. The opening and function-alization by oxidation of the nanotube array allows for the efficient immobilization of the model enzyme, glucose oxidase. The carboxylated open-ends of nanotubes are used for the immobilization of the enzymes, while the platinum substrate provides the direct transduction platform for signal monitoring. It is also shown that carbon nanotubes can play a dual role, both as immobilization matrices and as mediators, allowing for the development of a third generation of biosensor systems, with good overall analytical characteristics.
引用
收藏
页码:103 / 105
页数:3
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