The Infrapatellar Adipose Body: A Histotopographic Study

被引:48
作者
Macchi, Veronica [1 ]
Porzionato, Andrea [1 ]
Sarasin, Gloria [1 ]
Petrelli, Lucia [1 ]
Guidolin, Diego [1 ]
Rossato, Marco [2 ]
Fontanella, Chiara Giulia [3 ]
Natali, Arturo [3 ]
De Caro, Raffaele [1 ]
机构
[1] Univ Padua, Dept Mol Med, Inst Human Anat, Via A Gabelli 65, IT-35127 Padua, Italy
[2] Univ Padua, Clin Internal Med, IT-35127 Padua, Italy
[3] Univ Padua, Ctr Mech Biol Mat, IT-35127 Padua, Italy
关键词
Adipocytes; Morphometry; Microscopic anatomy; Knee; Hoffa's fat pad; FAT PAD; IMAGE-ANALYSIS; KNEE-JOINT; TISSUE; OSTEOARTHRITIS; FIBROSIS; OBESITY; CELLS;
D O I
10.1159/000442876
中图分类号
R602 [外科病理学、解剖学]; R32 [人体形态学];
学科分类号
100123 [人体微生态学]; 100210 [外科学];
摘要
The infrapatellar fat pad (IFP) can be regarded as a peculiar form of fibro-adipose tissue localized close to the synovial membrane and articular cartilage. The aims of the present study were to analyze the microscopic anatomy of the IFP through histological and ultrastructural methods, comparing it with that of the subcutaneous tissue of the abdomen and of the knee. Ten specimens of IFP were sampled from bodies of the Donation Program of the University of Padua without a history of osteoarthritis. The IFP consisted of white adipose tissue, of lobular type, with lobules delimited by thin connective septa. The IFP lobule areas were smaller (p < 0.05) and the interlobular septa were thicker (p > 0.05) than those of subcutaneous tissues of the abdomen, whereas the IFP lobule areas were larger (p < 0.05) and the interlobular septa were thinner than those of the subcutaneous tissue of the knee (p < 0.05). The IFP adipocytes present a mean area of 3,708 +/- 976 mu m(2) with a large intercellular space, whereas the mean area of the abdominal tissues was greater (6,082 +/- 628 mu m(2); p < 0.05). At scanning electron microscopythe IFP adipocytes were covered by thick fibrillary sheaths, creating a basket around the adipocytes. The structural characteristics of the IFP (lobular aspect of the adipose tissue, thickness of the septa with scarce elastic fibers) could act as a plastic portion aimed at the absorption of pressure variation during knee articular activity. The extensive distribution of nerves suggests a possible role of the IFP as a mechanoreceptor, corresponding to a tridimensional connective mesh working in the proprioceptive regulation of the activity of the knee joint. (C) 2016 S. Karger AG, Basel
引用
收藏
页码:220 / 231
页数:12
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