Convenient access to primary amines by employing the Barbier-type reaction of N-(trimethylsilyl)imines derived from aromatic and aliphatic aldehydes

被引：23

作者：

Gyenes, F ^{[1
]}

Bergmann, KE ^{[1
]}

Welch, JT ^{[1
]}

机构：

[1] SUNY Albany, Dept Chem, Albany, NY 12222 USA

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1998年 / 63卷 / 09期

关键词：

D O I：

10.1021/jo971061r

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new versatile preparation of primary amines via benzylation of aromatic and aliphatic aldimines is described. Sonochemical and traditional methods for generation of the reactive intermediates are compared and contrasted. Competitive reactions were analyzed via free energy relationships to support the proposed alkylative mechanism.

引用

页码：2824 / 2828

页数：5

共 43 条

[1]

[Anonymous], ADV ORGANIC CHEM REA

[2]

Barbier P., 1899, CR HEBD ACAD SCI, V128, P110

[3]

BAUER P, 1978, TETRAHEDRON LETT, P4853

[4]

BLOMBERG C, 1977, SYNTHESIS-STUTTGART, P18