Amygdala reactivity to emotional faces at high and low intensity in generalized social phobia: A 4-Tesla functional MRI study

被引：81

作者：

Yoon, K. Lira

Fitzgerald, Daniel A.

Angstadt, Mike

McCarron, Rosemary A.

Phan, K. Luan

机构：

[1] Univ Chicago, Dept Psychiat, Brain Imaging & Emot Lab, Div Biol Sci, Chicago, IL 60637 USA

[2] Univ Chicago, Pritzker Sch Med, Chicago, IL 60637 USA

[3] Univ Chicago, Ctr Cognit & Social Neurosci, Chicago, IL 60637 USA

来源：

PSYCHIATRY RESEARCH-NEUROIMAGING | 2007年 / 154卷 / 01期

关键词：

functional magnetic resonance imaging; social phobia; amygdala; MEDIAL PREFRONTAL CORTEX; BRAIN ACTIVATION; FEARFUL FACES; RESPONSES; ANXIETY; BIAS; THREAT; MEMORY; FMRI; EXPRESSIONS;

D O I：

10.1016/j.pscychresns.2006.05.004

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Using functional magnetic resonance imaging, we measured amygdala reactivity to faces varying on emotional intensity in subjects with generalized social phobia (GSP) and matched healthy controls, and observed greater bilateral activation to high (vs. low) intensity expressions in the phobic group, suggesting that more arousing social-emotional cues contribute to limbic hyperactivity in GSP. (c) 2006 Elsevier Ireland Ltd. All rights reserved.

引用

页码：93 / 98

页数：6

共 40 条

[1]

Adolphs R, 2003, ANN NY ACAD SCI, V985, P326

[2] Dissociated neural representations of intensity and valence in human olfaction [J].