Synthesis antimicrobial and antifungal activity of some new 3-substituted derivatives of 4-(2,4-dichlorophenyl)-5-adamantyl-1H-1,2,4-triazole

被引：119

作者：

Papakonstantinou-Garoufalias, S ^{[1
]}

Pouli, N

Marakos, P

Chytyroglou-Ladas, A

机构：

[1] Univ Athens, Div Pharmaceut Chem, Dept Pharm, Athens 15771, Greece

[2] Univ Athens, Div Microbiol, Sch Med, Athens 11527, Greece

来源：

FARMACO | 2002年 / 57卷 / 12期

关键词：

substituted 1,2,4-triazoles; antimicrobial activity; antifungal activity;

D O I：

10.1016/S0014-827X(02)01227-2

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

The synthesis of a series of substituted hydrazones and thiazolidinones is described, starting from N-[4-(2,4-dichlorophenyl)-5-adamantyl-1H-1,2,4-triazol-3-ylmercaptoacetyl)hydrazine. The new compounds were tested for antimicrobial and antifungal activity and some of them exhibited moderate activity against Candida albicans. (C) 2002 Editions scientifiques et medicales Elsevier SAS. All rights reserved.

引用

页码：973 / 977

页数：5

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