Integration of four genes, a pseudogene, thirty-one STSs, and a highly polymorphic STRP into the 7-10 Mb YAC contig of 5q34-q35

被引：8

作者：

Kostrzewa, M

Grady, DL

Moyzis, RK

Floter, L

Muller, U

机构：

[1] UNIV GIESSEN,INST HUMAN GENET,D-35392 GIESSEN,GERMANY

[2] LOS ALAMOS NATL LAB,CTR HUMAN GENOME STUDIES,LOS ALAMOS,NM 87545

来源：

HUMAN GENETICS | 1996年 / 97卷 / 03期

关键词：

D O I：

10.1007/s004390050060

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

Thirty-one sequence tagged sites and a highly polymorphic short tandem repeat polymorphism have been isolated from 5q34-q35 and integrated into the yeast artificial chromosome (YAC) contig of 5q34-q35. In addition, four genes (MSX2, CSX, DRD1, and CL100) and a pseudogene (GLUT6) were localized on this map. The high density of new markers in the region allowed further refinement of the YAC contig of distal 5q. This is a prerequisite for the conversion of this YAC into a cosmid contig.

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页码：399 / 403

页数：5

相关论文

共 18 条

[11] ASSIGNMENT OF A GENE LOCUS INVOLVED IN CRANIOSYNOSTOSIS TO CHROMOSOME-5QTER [J].

MULLER, U ;

WARMAN, ML ;

MULLIKEN, JB ;

WEBER, JL .

HUMAN MOLECULAR GENETICS, 1993, 2 (02) :119-122

[12] A PHYSICAL MAP OF 15 LOCI ON HUMAN CHROMOSOME-5Q23-Q33 BY 2-COLOR FLUORESCENCE INSITU HYBRIDIZATION [J].

SALTMAN, DL ;

DOLGANOV, GM ;

WARRINGTON, JA ;

WASMUTH, JJ ;

LOVETT, M .

GENOMICS, 1993, 16 (03) :726-732

[13] THE STRUCTURE AND FUNCTION OF THE HOMEODOMAIN [J].

SCOTT, MP ;

TAMKUN, JW ;

HARTZELL, GW .

BIOCHIMICA ET BIOPHYSICA ACTA, 1989, 989 (01) :25-48

[14] ASSIGNMENT OF CARDIAC HOMEOBOX GENE CSX TO HUMAN-CHROMOSOME 5Q34 [J].

SHIOJIMA, I ;

KOMURO, I ;

INAZAWA, J ;

NAKAHORI, Y ;

MATSUSHITA, I ;

ABE, T ;

NAGAI, R ;

YAZAKI, Y .

GENOMICS, 1995, 27 (01) :204-206

[15] A PROCEDURE FOR INVITRO AMPLIFICATION OF DNA SEGMENTS THAT LIE OUTSIDE THE BOUNDARIES OF KNOWN SEQUENCES [J].

TRIGLIA, T ;

PETERSON, MG ;

KEMP, DJ .

NUCLEIC ACIDS RESEARCH, 1988, 16 (16) :8186-8186

[16] A RADIATION HYBRID MAP OF 18 GROWTH-FACTOR, GROWTH-FACTOR RECEPTOR, HORMONE RECEPTOR, OR NEUROTRANSMITTER RECEPTOR GENES ON THE DISTAL REGION OF THE LONG ARM OF CHROMOSOME-5 [J].

WARRINGTON, JA ;

BAILEY, SK ;

ARMSTRONG, E ;

APRELIKOVA, O ;

ALITALO, K ;

DOLGANOV, GM ;

WILCOX, AS ;

SIKELA, JM ;

WOLFE, SF ;

LOVETT, M ;

WASMUTH, JJ .

GENOMICS, 1992, 13 (03) :803-808

[17] MAPPING OF HUMAN CHROMOSOME-5 MICROSATELLITE DNA POLYMORPHISMS [J].

WEBER, JL ;

POLYMEROPOULOS, MH ;

MAY, PE ;

KWITEK, AE ;

XIAO, H ;

MCPHERSON, JD ;

WASMUTH, JJ .

GENOMICS, 1991, 11 (03) :695-700

[18] A 2ND-GENERATION LINKAGE MAP OF THE HUMAN GENOME [J].

WEISSENBACH, J ;

GYAPAY, G ;

DIB, C ;

VIGNAL, A ;

MORISSETTE, J ;

MILLASSEAU, P ;

VAYSSEIX, G ;

LATHROP, M .

NATURE, 1992, 359 (6398) :794-801