Non-alcoholic steatohepatitis in children and adolescents

被引：93

作者：

Manton, ND

Lipsett, J

Moore, DJ

Davidson, GP

Bourne, AJ

Couper, RTL

机构：

[1] Womens & Childrens Hosp, Dept Histopathol, Adelaide, SA, Australia

[2] Womens & Childrens Hosp, Dept Gastroenterol, Adelaide, SA, Australia

来源：

MEDICAL JOURNAL OF AUSTRALIA | 2000年 / 173卷 / 09期

关键词：

D O I：

10.5694/j.1326-5377.2000.tb139299.x

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

We describe 17 children with non-alcoholic steatohepatitis. All had elevated levels of serum liver enzymes and 16 were morbidly obese. Liver biopsy showed variable steatosis and fibrosis in nine patients. At follow-up, 12 of 14 patients had persistent morbid obesity and II had elevated liver enzyme levels.

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页码：476 / 479

页数：20

相关论文

共 20 条

[1]

BACON B, 1995, HEPATOLOGY, V21, P1742

[2] IDIOPATHIC STEATOHEPATITIS IN CHILDHOOD - A MULTICENTER RETROSPECTIVE STUDY [J].

BALDRIDGE, AD ;

PEREZATAYDE, AR ;

GRAEMECOOK, F ;

HIGGINS, L ;

LAVINE, JE .

JOURNAL OF PEDIATRICS, 1995, 127 (05) :700-704

[3] Cryptogenic cirrhosis: Clinical characterization and risk factors for underlying disease [J].

Caldwell, SH ;

Oelsner, DH ;

Iezzoni, JC ;

Hespenheide, EE ;

Battle, EH ;

Driscoll, CJ .

HEPATOLOGY, 1999, 29 (03) :664-669

[4] Alterations in liver ATP homeostasis in human nonalcoholic steatohepatitis - A pilot study [J].

Cortez-Pinto, H ;

Chatham, J ;

Chacko, VP ;

Arnold, C ;

Rashid, A ;

Diehl, AM .

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1999, 282 (17) :1659-1664

[5] Liver involvement in obese children: Ultrasonography and liver enzyme levels at diagnosis and during follow-up in an Italian population [J].

Franzese A. ;

Vajro P. ;

Argenziano A. ;

Puzziello A. ;

Iannucci M.P. ;

Saviano M.C. ;

Brunetti F. ;

Rubino A. .

Digestive Diseases and Sciences, 1997, 42 (7) :1428-1432

[6]

HAMILL PVV, DHEW PUBLICATION PHS

[7] Recurrence of nonalcoholic steatohepatitis following liver transplantation [J].

Kim, WR ;

Poterucha, JJ ;

Porayko, MK ;

Dickson, ER ;

Steers, JL ;

Wiesner, RH .

TRANSPLANTATION, 1996, 62 (12) :1802-1805

[8]

Laurin J, 1996, HEPATOLOGY, V23, P1464

[9] Relative antioxidant deficiency in obese children: A weighty contributor to morbidity? [J].

Lavine, JE .

JOURNAL OF PEDIATRICS, 1999, 134 (02) :132-133

[10] Change in body mass index in Australian primary school children, 1985-1997 [J].

Lazarus, R ;

Wake, M ;

Hesketh, K ;

Waters, E .

INTERNATIONAL JOURNAL OF OBESITY, 2000, 24 (06) :679-684