Enhancement of chrysogenin production in cultures of Penicillium chrysogenum by uronic acid oligosaccharides

被引:33
作者
Asilonu, E [1 ]
Bucke, C [1 ]
Keshavarz, T [1 ]
机构
[1] Univ Westminster, Dept Biotechnol, Fungal Biotechnol Grp, London W1M 8JS, England
关键词
chrysogenin; elicitors; enhancement; oligosaccharides; Penicillium chrysogenum;
D O I
10.1023/A:1005694415666
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 [微生物学]; 0836 [生物工程]; 090102 [作物遗传育种]; 100705 [微生物与生化药学];
摘要
Additions of 50 to 100 mu g of acid-hydrolysed alginate oligosaccharides ml(-1) and enzyme-hydrolysed pectin oligosaccharides to 24- to 48-h cultures of Penicillium chrysogenum, ATCC 9480, led to enhanced production of chrysogenin by over 30 to 40% in shaken flasks and bioreactors. Some of the oligosaccharides also promoted biomass formation but were not used as a carbon source.
引用
收藏
页码:931 / 936
页数:6
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