Canonical and unconventional pairing schemes between bis(nucleobase) complexes of trans-a2PtII:: Artificial nucleobase quartets and C-H. . .N bonds

被引：32

作者：

Freisinger, E ^{[1
]}

Rother, IB ^{[1
]}

Lüth, MS ^{[1
]}

Lippert, B ^{[1
]}

机构：

[1] Univ Dortmund, Fachbereich Chem, D-44221 Dortmund, Germany

来源：

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA | 2003年 / 100卷 / 07期

关键词：

H bonding; platinum;

D O I：

10.1073/pnas.0436700100

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

If two nucleobases are crosslinked by trans-a(2)Pt(II), self-association via H bonding may take place either through individual bases or jointly through both bases. Due to the blockage of an acceptor site by the metal, the number of feasible pairing patterns can be reduced, and the preferred ones altered. If the metalated base pair as a whole undergoes association, base quartets can form. Various scenarios resulting from the application of guanine, hypoxanthine, and cytosine model nucleobases are discussed. Unconventional C-H...N hydrogen bonding has been observed in several instances.

引用

页码：3748 / 3753

页数：6

共 55 条

[1] STRUCTURE OF BIS(9-METHYLHYPOXANTHINE)SILVER(I) NITRATE DIHYDRATE, [AG(C6H6N4O)2](NO3).2H2O [J].

AOKI, K ;

SAENGER, W .

ACTA CRYSTALLOGRAPHICA SECTION C-CRYSTAL STRUCTURE COMMUNICATIONS, 1984, 40 (MAY) :772-775

[2] STRUCTURE OF POLYDEOXYGUANYLIC ACID POLYDEOXYCYTIDYLIC ACID [J].

ARNOTT, S ;

SELSING, E .

JOURNAL OF MOLECULAR BIOLOGY, 1974, 88 (02) :551-552

[3] STRUCTURES FOR POLYINOSINIC ACID AND POLYGUANYLIC ACID [J].

ARNOTT, S ;

CHANDRASEKARAN, R ;

MARTTILA, CM .

BIOCHEMICAL JOURNAL, 1974, 141 (02) :537-+

[4] CRYSTAL-STRUCTURES OF 2 PT(II) DIAMINE COMPOUNDS - TRANS-PT(CH3NH2)2CL2 AND CIS-PT[(CH3)2NH]2CL2 [J].

ARPALAHTI, J ;

LIPPERT, B ;

SCHOLLHORN, H ;

THEWALT, U .

INORGANICA CHIMICA ACTA-BIOINORGANIC CHEMISTRY, 1988, 153 (01) :45-49

[5] Functional and dysfunctional roles of quadruplex DNA in cells [J].

Arthanari, H ;

Bolton, PH .

CHEMISTRY & BIOLOGY, 2001, 8 (03) :221-230

[6] CRYSTAL-STRUCTURE OF BIS(9-METHYLHYPOXANTHINE)SILVER(I) PERCHLORATE MONOHYDRATE, A MODEL COMPLEX FOR THE SILVER-POLY(I) SYSTEM [J].

BELANGERGARIEPY, F ;

BEAUCHAMP, AL .

JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1980, 102 (10) :3461-3464

[7] C-H...O and C-H...N interactions in RNA structures [J].

Brandl, M ;

Lindauer, K ;

Meyer, M ;

Sühnel, J .

THEORETICAL CHEMISTRY ACCOUNTS, 1999, 101 (1-3) :103-113

[8]

Brown T, 1997, BIOPOLYMERS, V44, P91, DOI 10.1002/(SICI)1097-0282(1997)44:1<91::AID-BIP6>3.0.CO

[9]

2-V

[10] MULTIDIMENSIONAL CRYSTAL ENGINEERING OF BIFUNCTIONAL METAL-COMPLEXES CONTAINING COMPLEMENTARY TRIPLE HYDROGEN-BONDS [J].

BURROWS, AD ;

CHAN, CW ;

CHOWDHRY, MM ;

MCGRADY, JE ;

MINGOS, DMP .

CHEMICAL SOCIETY REVIEWS, 1995, 24 (05) :329-&

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