2H-Pyrazol-3-ylamines as precursors for the synthesis of polyfunctionally substituted pyrazolo[1,5-a]pyrimidines

被引：28

作者：

Anwar, Hany Fakhry ^{[1
]}

Fleita, Daisy Hanna

Kolshorn, Heinz

Meier, Herbert

Elnagdi, Mohamed Hilmy

机构：

[1] Cairo Univ, Fac Sci, Dept Chem, Giza, Egypt

[2] Amer Univ Cairo, Dept Chem, Cairo, Egypt

[3] Johannes Gutenberg Univ Mainz, Inst Organ Chem, D-6500 Mainz, Germany

来源：

ARKIVOC | 2006年

关键词：

7-aminopyrazolo[1,5-a] pyrimidines; amino-imine tautomerism; HMBC; HMQC experiments;

D O I：

10.3998/ark.5550190.0007.f16

中图分类号：

O62 [有机化学];

学科分类号：

070303 [有机化学]; 081704 [应用化学];

摘要：

Substituted aminopyrazoles (5a-d) were synthesized and reacted with bidentate electrophiles to afford pyrazolo[1,5-alpha] pyrimidines. The regioorientation of reagents has been determined by (N-15, H-1) HMBC measurements as well as an X-ray crystal structure determination.

引用

收藏

页码：133 / 141

页数：9

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