Inflammation and cancer: the long reach of Ras

被引：78

作者：

Karin, M ^{[1
]}

机构：

[1] Univ Calif San Diego, Sch Med, Dept Pharmacol, La Jolla, CA 92093 USA

来源：

NATURE MEDICINE | 2005年 / 11卷 / 01期

关键词：

D O I：

10.1038/nm0105-20

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

For decades cancer biologists have thought of oncogenes in terms of their ability to prompt tumor growth and survival, acting within the cancer cell. That viewpoint is now changing to take into account data showing that oncogenes influence inflammation. Insights now emerge from work on Ras and the proinflammatory mediator interleukin-8, produced by tumor-infiltrating immune cells.

引用

页码：20 / 21

页数：2

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