Anatomy and physiology of female sexual function and dysfunction - Classification, evaluation and treatment options

被引:92
作者
Berman, JR [1 ]
Adhikari, SP [1 ]
Goldstein, I [1 ]
机构
[1] Boston Univ, Sch Med, Dept Urol, Womens Sexual Hlth Clin, Boston, MA 02118 USA
关键词
female sexual dysfunction; anatomy; physiology; menopause;
D O I
10.1159/000020247
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Female sexual dysfunction is a significant age-related, progressive and highly prevalent problem that affects a substantial number of women in the United States. The female sexual response cycle is initiated by neurotransmitter-mediated vascular and nonvascular smooth muscle relaxation resulting in increased pelvic blood flow, vaginal lubrication, and clitoral and labial engorgement. These mechanisms are mediated by a combination of neuromuscular and vasocongestive events. Physiological impairments that interfere with the normal female sexual response bring about complaints associated with diminished sexual arousal, libido, vaginal lubrication, genital sensation, and ability to achieve orgasm. Therapy aimed at restoring hormone levels as well as genital blood flow will be discussed. Copyright (C) 2000 S. Karger AG, Basel.
引用
收藏
页码:20 / 29
页数:10
相关论文
共 39 条
[1]   A comparative study of safety and efficacy of continuous low dose oestradiol released from a vaginal ring compared with conjugated equine oestrogen vaginal cream in the treatment of postmenopausal urogenital atrophy [J].
Ayton, RA ;
Darling, GM ;
Murkies, AL ;
Farrell, EA ;
Weisberg, E ;
Selinus, I ;
Fraser, IS .
BRITISH JOURNAL OF OBSTETRICS AND GYNAECOLOGY, 1996, 103 (04) :351-358
[2]  
Bancroft J., 1989, Human sexuality and its problems, V2nd
[3]   Report of the international consensus development conference on female sexual dysfunction: Definitions and classifications [J].
Basson, R ;
Berman, J ;
Burnett, A ;
Derogatis, L ;
Ferguson, D ;
Fourcroy, J ;
Goldstein, I ;
Graziottin, A ;
Heiman, J ;
Laan, E ;
Leiblum, S ;
Padma-Nathan, H ;
Rosen, R ;
Segraves, K ;
Segraves, RT ;
Shabsigh, R ;
Sipski, M ;
Wagner, G ;
Whipple, B .
JOURNAL OF UROLOGY, 2000, 163 (03) :888-893
[4]   Effect of estrogen withdrawal on nitric oxide synthase expression and apoptosis in the rat vagina [J].
Berman, JR ;
McCarthy, MM ;
Kyprianou, N .
UROLOGY, 1998, 51 (04) :650-656
[5]   Female sexual dysfunction: Incidence, pathophysiology, evaluation, and treatment options [J].
Berman, JR ;
Berman, L ;
Goldstein, I .
UROLOGY, 1999, 54 (03) :385-391
[6]   Immunohistochemical description of nitric oxide synthase isoforms in human clitoris [J].
Burnett, AL ;
Calvin, DC ;
Silver, RI ;
Peppas, DS ;
Docimo, SG .
JOURNAL OF UROLOGY, 1997, 158 (01) :75-78
[7]   REPRODUCTIVE HEALTH, USE OF ESTROGEN AND EXPERIENCE OF SYMPTOMS IN PERIMENOPAUSAL WOMEN - A POPULATION-BASED STUDY [J].
COLLINS, A ;
LANDGREN, BM .
MATURITAS, 1994, 20 (2-3) :101-111
[8]  
Goldstein I, 1998, INT J IMPOT RES, V10, pS84
[9]  
HILLIGES M, 1995, ACTA ANAT, V153, P119
[10]  
Kaplan HS, 1974, NEW SEX THERAPY