A convenient synthesis of 4-aminoaryl substituted cyclic imides

被引：30

作者：

Mederski, WWKR ^{[1
]}

Baumgarth, M ^{[1
]}

Germann, M ^{[1
]}

Kux, D ^{[1
]}

Weitzel, T ^{[1
]}

机构：

[1] Merck KGaA, Preclin Pharmaceut Res, D-64271 Darmstadt, Germany

来源：

TETRAHEDRON LETTERS | 2003年 / 44卷 / 10期

关键词：

condensations; cyclisation; N-imides; nitro compounds;

D O I：

10.1016/S0040-4039(03)00167-9

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

An efficient one-step synthesis of 4-nitro-N-aryl substituted glutarimides, succinimides and maleimides in polyphosphoric acid is described together with the subsequent reduction to the corresponding anilines. The scope and limitation of this cyclocondensation are presented. (C) 2003 Elsevier Science Ltd. All rights reserved.

引用

页码：2133 / 2136

页数：4

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