Maternal serum transformed α-fetoprotein levels in women with intrauterine growth retardation

被引：8

作者：

Bartha, Jose L. ^{[1
]}

Illanes, Sebastian ^{[1
]}

Gonzalez-Bugatto, Fernando ^{[1
]}

Abdel-Fattah, Sherif A. ^{[1
]}

Mizejewski, Gerald J. ^{[1
]}

Soothill, Peter W. ^{[1
]}

机构：

[1] Univ Bristol, St Michaels Hosp, Fetal Med Res Unit, Dept Obstet & Gynaecol, Bristol, Avon, England

来源：

FETAL DIAGNOSIS AND THERAPY | 2007年 / 22卷 / 04期

关键词：

alpha-fetoprotein; growth retardation; pregnancy complications;

D O I：

10.1159/000100794

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

Objective: To evaluate maternal serum transformed alpha-fetoprotein (t-AFP) levels in women with intrauterine growth retardation (IUGR). Methods: 60 pregnant women in two groups were studied: 30 with IUGR and 30 healthy pregnant women as a control group. t-AFP concentrations were determined by ELISA assay. Results: Maternal serum t-AFP levels were higher in women with IUGR than in the control group: 15.39 (10.81-24.01) ng/ml vs. 8.66 (6.22-13.45) ng/ml (p= 0.003). t-AFP levels were even higher in those with fetal hemodynamic redistribution 21.08 (16.02-40.85) ng/ml than in those without 12.15 (10.48-17.45) ng/ml (p = 0.03). Conclusions: Maternal serum t-AFP is increased in women with IUGR and this elevation is marked in those with fetal hemodynamic redistribution. Copyright (c) 2007 S. Karger AG, Basel.

引用

页码：294 / 298

页数：5

共 17 条

[1] Cord blood α-fetoprotein concentrations in term newborns of smoking mothers [J].