Prediction of 7 months methadone maintenance treatment response by four measures of antisociality

被引:59
作者
Alterman, AI
Rutherford, MJ
Cacciola, JS
McKay, JR
Boardman, CR
机构
[1] Univ Penn, Dept Med, Sch Med, Treatment Res Ctr, Philadelphia, PA 19104 USA
[2] Childrens Hosp, Div Biostat & Epidemiol, Penna, PA USA
关键词
antisociality; methadone; treatment response;
D O I
10.1016/S0376-8716(98)00015-5
中图分类号
R194 [卫生标准、卫生检查、医药管理];
学科分类号
摘要
Zero-order correlational and simultaneous regression analyses were performed to ascertain the comparative validity of four measures of antisociality for predicting the initial 7 months treatment response of 193 male methadone maintenance (MM) patients. Predictor variables were the number of childhood conduct disorder (CD) behaviors, number of adult antisocial personality disorder (A-APD) behaviors, the revised Psychopathy Checklist (PCL-R) score and the revised California Psychological Inventory-Socialization (CPI-So) scale score. The outcome measures were completion/noncompletion of 7 months of treatment, percent positive during-treatment of cocaine, opiate and benzodiazepine urine toxicologies, and change from baseline to 7 months follow-up in seven Addiction severity index (ASI) composite scores (CSs). All four measures of antisociality were significantly correlated with treatment noncompletion, although only the PCL-R score was significant in the predictor model. The PCL-R predicted more positive cocaine urines. At the individual level, both PCL-R and CPI-So were associated with more positive benzodiazepine urines, but neither contributed a significant amount of variance when both were entered in the model. None of the predictors were significantly associated with self reported improvement in the CSs. The PCL-R and CPI-So were more successful in predicting outcomes than the two behavior-based measures. (C) 1998 Elsevier Science Ireland Ltd. All rights reserved.
引用
收藏
页码:217 / 223
页数:7
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