Mikanolide from Jamaican Mikania micrantha

被引：16

作者：

Bakir, M ^{[1
]}

Facey, PC ^{[1
]}

Hassan, I ^{[1
]}

Mulder, WH ^{[1
]}

Porter, RB ^{[1
]}

机构：

[1] Univ W Indies, Dept Chem, Kingston 7, Jamaica

来源：

ACTA CRYSTALLOGRAPHICA SECTION C-STRUCTURAL CHEMISTRY | 2004年 / 60卷 / 11期

关键词：

Antibiotics - Composition - Crystal structure - DNA - Hydrogen bonds - Parameter estimation - Torsional stress;

D O I：

10.1107/S0108270104017809

中图分类号：

O6 [化学];

学科分类号：

0703 [化学];

摘要：

Mikanolide [systematic names: 1,10: 2,3-diepoxy-6,8-dihydroxy-11-vinylgermacr-4-ene 12,14-di-gamma-lactone and 7,10a-dimethyl-1a,1b,2a,6a,7,9a,10,10a-octahydro-4H-6,3-methenofuro[3,2-c]bisoxireno[f,h]oxacycloundecin-4,8(6H)-dione], C15H14O6, derived from a variety of Mikania micrantha growing in Portland, Jamaica, contains a methylcyclodecane ring fused to an unsaturated planar alpha,gamma-lactone, an envelope-type near-planar vinyl-beta,gamma-lactone and two epoxide moieties. The crystal packing shows stacks of mikanolide molecules interlocked via a network of non-classical C-H...O hydrogen bonds between the lactone units.

引用

页码：O798 / O800

页数：3

共 15 条

[1]

GERMACRANOLIDES OF MIKANIA-CORDATA [J].