Roles of mast cells and basophils in innate and acquired immunity

被引：277

作者：

Wedemeyer, J ^{[1
]}

Tsai, M ^{[1
]}

Galli, SJ ^{[1
]}

机构：

[1] Stanford Univ, Med Ctr, Dept Pathol, Stanford, CA 94305 USA

来源：

CURRENT OPINION IN IMMUNOLOGY | 2000年 / 12卷 / 06期

关键词：

D O I：

10.1016/S0952-7915(00)00154-0

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

There have been several recent advances in knowledge about mast cells and basophils in immune responses, of which some are particularly important: a role has been found for heparin in the storage of certain proteases and other mediators in mast cell cytoplasmic granules; an important role for mast cells in the development of several chronic aspects of an asthma model in mice has been discovered;: and a new approach has been developed, based on the generation of mast cells from embryonic stem cells in vitro, to investigate mast cell function in vitro or in vivo.

引用

页码：624 / 631

页数：8

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