The ATRs, ATMs, and TORs are giant HEAT repeat proteins

被引:214
作者
Perry, J [1 ]
Kleckner, N [1 ]
机构
[1] Harvard Univ, Dept Mol & Cellular Biol, Cambridge, MA 02138 USA
关键词
D O I
10.1016/S0092-8674(03)00033-3
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
引用
收藏
页码:151 / 155
页数:5
相关论文
共 21 条
[1]   Cell cycle checkpoint signaling through the ATM and ATR kinases [J].
Abraham, RT .
GENES & DEVELOPMENT, 2001, 15 (17) :2177-2196
[2]   HEAT REPEATS IN THE HUNTINGTONS-DISEASE PROTEIN [J].
ANDRADE, MA ;
BORK, P .
NATURE GENETICS, 1995, 11 (02) :115-116
[3]   Comparison of ARM and HEAT protein repeats [J].
Andrade, MA ;
Petosa, C ;
O'Donoghue, SI ;
Müller, CW ;
Bork, P .
JOURNAL OF MOLECULAR BIOLOGY, 2001, 309 (01) :1-18
[4]   Protein repeats: Structures, functions, and evolution [J].
Andrade, MA ;
Perez-Iratxeta, C ;
Ponting, CP .
JOURNAL OF STRUCTURAL BIOLOGY, 2001, 134 (2-3) :117-131
[5]   ATR homolog Mec1 promotes fork progression, thus averting breaks in replication slow zones [J].
Cha, RS ;
Kleckner, N .
SCIENCE, 2002, 297 (5581) :602-606
[6]   Structure of the FKBP12-rapamycin complex interacting with the binding domain of human FRAP [J].
Choi, JW ;
Chen, J ;
Schreiber, SL ;
Clardy, J .
SCIENCE, 1996, 273 (5272) :239-242
[7]   Structure of the nuclear transport complex karyopherin-β2-Ran•GppNHp [J].
Chook, YM ;
Blobel, G .
NATURE, 1999, 399 (6733) :230-237
[8]   Structure of importin-β bound to tbe IBB domain of importin-α [J].
Cingolani, G ;
Petosa, C ;
Weis, K ;
Müller, CW .
NATURE, 1999, 399 (6733) :221-229
[9]   Crystallographic analysis of the recognition of a nuclear localization signal by the nuclear import factor karyopherin α [J].
Conti, E ;
Uy, M ;
Leighton, L ;
Blobel, G ;
Kuriyan, J .
CELL, 1998, 94 (02) :193-204
[10]   ATR and ATRIP: Partners in checkpoint signaling [J].
Cortez, D ;
Guntuku, S ;
Qin, J ;
Elledge, SJ .
SCIENCE, 2001, 294 (5547) :1713-1716