Remission of Philadelphia chromosome-positive central nervous system leukemia after dasatinib therapy

被引：18

作者：

Abdelhalim, Ahmed

Barcos, Maurice

Block, Annemarie W.

Sait, Sheila N. J.

Starostik, Petr

Wetzler, Meir

Wang, Eunice S. ^{[1
]}

机构：

[1] Roswell Pk Canc Inst, Dept Med, Leukemia Serv, Buffalo, NY 14263 USA

[2] Roswell Pk Canc Inst, Dept Radiol, Buffalo, NY 14263 USA

[3] Roswell Pk Canc Inst, Dept Pathol & Lab Med, Buffalo, NY 14263 USA

[4] SUNY Buffalo, Sch Med & Biomed Sci, Dept Med, Buffalo, NY 14260 USA

来源：

LEUKEMIA & LYMPHOMA | 2007年 / 48卷 / 05期

关键词：

D O I：

10.1080/10428190701258370

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：1053 / 1056

页数：4

共 12 条

[1]

BLEYER WA, 1978, BLOOD, V51, P835

[2] Potent inhibition of platelet-derived growth factor-induced responses in vascular smooth muscle cells by BMS-354825 (dasatinib) [J].

Chen, ZM ;

Lee, FY ;

Bhalla, KN ;

Wu, J .

MOLECULAR PHARMACOLOGY, 2006, 69 (05) :1527-1533

[3]

Fleischhack G, 2005, CLIN PHARMACOKINET, V44, P1, DOI 10.2165/00003088-200544010-00001

[4] Pharmacokinetics and cellular uptake of imatinib and its main metabolite CGP74588 [J].

le Coutre, P ;

Kreuzer, KA ;

Pursche, S ;

von Bonin, M ;

Leopold, T ;

Baskaynak, G ;

Dörken, B ;

Ehninger, G ;

Ottmann, O ;

Jenke, A ;

Bornhäuser, M ;

Schleyer, E .

CANCER CHEMOTHERAPY AND PHARMACOLOGY, 2004, 53 (04) :313-323

[5] Action of the Src family kinase inhibitor, dasatinib (BMS-354825), on human prostate cancer cells [J].

Nam, S ;

Kim, DW ;

Cheng, JQ ;

Zhang, SM ;

Lee, JH ;

Buettner, R ;

Mirosevich, J ;

Lee, FY ;

Jove, R .

CANCER RESEARCH, 2005, 65 (20) :9185-9189

[6] Low concentrations of STI571 in the cerebrospinal fluid:: a case report [J].

Petzer, AL ;

Gunsilius, E ;

Hayes, M ;

Stockhammer, G ;

Duba, HC ;

Schneller, F ;

Grünewald, K ;

Poewe, W ;

Gastl, G .

BRITISH JOURNAL OF HAEMATOLOGY, 2002, 117 (03) :623-625

[7] Dasatinib (BMS-354825), a dual SRC/ABL kinase inhibitor, inhibits the kinase activity of wild-type, juxtamembrane, and activation loop mutant KIT Isoforms associated with human malignancies [J].

Schittenhelm, MM ;

Shiraga, S ;

Schroeder, A ;

Corbin, AS ;

Griffith, D ;

Lee, FY ;

Bokemeyer, C ;

Deininger, MWN ;

Druker, BJ ;

Heinrich, MC .

CANCER RESEARCH, 2006, 66 (01) :473-481

[8] Dasatinib (BMS-354825) selectively induces apoptosis in lung cancer cells dependent on epidermal growth factor receptor signaling for survival [J].

Song, Lanxi ;

Morris, Mark ;

Bagui, Tapan ;

Lee, Francis Y. ;

Jove, Richard ;

Haura, Eric B. .

CANCER RESEARCH, 2006, 66 (11) :5542-5548

[9] Imatinib mesylate has limited activity against the central nervous system involvement of Philadelphia chromosome-positive acute lymphoblastic leukaemia due to poor penetration into cerebrospinal fluid [J].

Takayama, N ;

Sato, N ;

O'Brien, SG ;

Ikeda, Y ;

Okamoto, SI .

BRITISH JOURNAL OF HAEMATOLOGY, 2002, 119 (01) :106-108

[10] Dasatinib in imatinib-resistant Philadelphia chromosome-positive leukemias [J].

Talpaz, Moshe ;

Shah, Neil P. ;

Kantarjian, Hagop ;

Donato, Nicholas ;

Nicoll, John ;

Paquette, Ron ;

Cortes, Jorge ;

O'Brien, Susan ;

Nicaise, Claude ;

Bleickardt, Eric ;

Blackwood-Chirchir, M. Anne ;

Iyer, Vishwanath ;

Chen, Tai-Tsang ;

Huang, Fei ;

Decillis, Arthur P. ;

Sawyers, Charles L. .

NEW ENGLAND JOURNAL OF MEDICINE, 2006, 354 (24) :2531-2541

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