Eaten to death

被引：21

作者：

Nelson, Charles ^{[1
]}

Baehrecke, Eric H. ^{[1
]}

机构：

[1] Univ Massachusetts, Sch Med, Dept Canc Biol, Worcester, MA 01605 USA

来源：

FEBS JOURNAL | 2014年 / 281卷 / 24期

关键词：

ATG genes; apoptosis; autophagy; cell death; necrosis; PROGRAMMED CELL-DEATH; GROWTH ARREST; STEROID REGULATION; AUTOPHAGY; MUTANTS; DIFFERENTIATION; DEGRADATION; STARVATION; CYTOPLASM; RECEPTOR;

D O I：

10.1111/febs.13114

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

070307 [化学生物学]; 071010 [生物化学与分子生物学];

摘要：

Macro-autophagy (hereafter referred to as autophagy) delivers cytoplasmic material to the lysosome for degradation, and has been implicated in many cellular processes, including stress, infection, survival and death. Although the regulation and role of autophagy in stress, infection and survival is apparent, its involvement during cell death remains relatively unclear. In this review, we highlight what is known about the role that autophagy can play during physiological cell death, and discuss the implications of better understanding cellular destruction that involves autophagy.

引用

页码：5411 / 5417

页数：7

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