The unusual transmembrane electron transporter DsbD and its homologues: a bacterial family of disulfide reductases

被引：35

作者：

Porat, A ^{[1
]}

Cho, SH ^{[1
]}

Beckwith, J ^{[1
]}

机构：

[1] Harvard Univ, Sch Med, Dept Microbiol & Mol Genet, Boston, MA 02115 USA

来源：

RESEARCH IN MICROBIOLOGY | 2004年 / 155卷 / 08期

关键词：

disulfide bond; dsbD; dsbC; disulfide reductase; electron transfer;

D O I：

10.1016/j.resmic.2004.05.005

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

The bacterial membrane protein DsbD transfers electrons across the cytoplasmic membrane to reduce protein disultide bonds in extracytoplasmic proteins. Its substrates include protein disulfide isomerases and a protein involved in cytochrome c assembly. Two membrane-embedded cysteines in DsbD alternate between the disulfide-bonded (oxidized) and reduced states in this process. (C) 2004 Elsevier SAS. All rights reserved.

引用

页码：617 / 622

页数：6

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