Application of a parallel synthetic approach in atom-transfer radical polymerization: Set-up and feasibility demonstration

被引：51

作者：

Zhang, HQ

Fijten, MWM

Hoogenboom, R

Reinierkens, R

Schubert, US

机构：

[1] Eindhoven Univ Technol, Lab Macromol Chem & Nanosci, NL-5600 MB Eindhoven, Netherlands

[2] Dutch Polymer Inst, NL-5600 MB Eindhoven, Netherlands

来源：

MACROMOLECULAR RAPID COMMUNICATIONS | 2003年 / 24卷 / 01期

关键词：

atom transfer radical polymerization (ATRP); automated purification; methyl methacrylate; online measurements; offline measurements; parallel synthesis;

D O I：

10.1002/marc.200390002

中图分类号：

O63 [高分子化学（高聚物）];

学科分类号：

070305 ; 080501 ; 081704 ;

摘要：

A parallel synthetic approach toward homogenous atom-transfer radical polymerization of methyl methacrylate has been successfully applied by utilizing an automated synthesizer. Experimental set-up, automated parallel synthesis and purification of the polymers via a solid-phase extraction set-up, as well as online and offline measurements of the molecular weights and monomer conversion are described in detail. In addition, a comparison with conventional experiments in the laboratory is provided.

引用

页码：81 / 86

页数：6

共 41 条

[1] Combinatorial materials science: What's new since Edison?
Amis, EJ
Xiang, XD
Zhao, JC
[J]. MRS BULLETIN, 2002, 27 (04) : 295 - 297
[2] High-throughput synthesis of nanoscale materials:: Structural optimization of functionalized one-step star polymers
Bosman, AW
Heumann, A
Klaerner, G
Benoit, D
Fréchet, JMJ
Hawker, CJ
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 2001, 123 (26) : 6461 - 6462
[3] A combinatorial approach for polymer design
Brocchini, S
James, K
Tangpasuthadol, V
Kohn, J
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1997, 119 (19) : 4553 - 4554
[4] CHARMOT D, 2001, POLYM PREPR AM CHEM, V42, P627
[5] CHARMOT D, 2002, Patent No. 6380335
[6] Living free-radical polymerization by reversible addition-fragmentation chain transfer: The RAFT process
Chiefari, J
Chong, YK
Ercole, F
Krstina, J
Jeffery, J
Le, TPT
Mayadunne, RTA
Meijs, GF
Moad, CL
Moad, G
Rizzardo, E
Thang, SH
[J]. MACROMOLECULES, 1998, 31 (16) : 5559 - 5562
[7] Destarac M, 2000, MACROMOL RAPID COMM, V21, P1337, DOI 10.1002/1521-3927(20001201)21:18<1337::AID-MARC1337>3.0.CO
[8] 2-7
[9] Soluble supports tailored for organic synthesis:: Parallel polymer synthesis via sequential normal/living free radical processes
Gravert, DJ
Datta, A
Wentworth, P
Janda, KD
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1998, 120 (37) : 9481 - 9495
[10] Atom transfer polymerization of methyl methacrylate mediated by alkylpyridylmethanimine type ligands, copper(I) bromide, and alkyl halides in hydrocarbon solution
Haddleton, DM
Crossman, MC
Dana, BH
Duncalf, DJ
Heming, AM
Kukulj, D
Shooter, AJ
[J]. MACROMOLECULES, 1999, 32 (07) : 2110 - 2119

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