Prostate cancer: are new prognostic markers on the horizon?

被引：7

作者：

Lijovic, M ^{[1
]}

Fabiani, ME ^{[1
]}

Bader, J ^{[1
]}

Frauman, AG ^{[1
]}

机构：

[1] Univ Melbourne, Austin & Repatriat Med Ctr, Mol Immunol Lab, Dept Med,Clin Pharmacol & Therapeut Unit, Heidelberg, Vic 3084, Australia

来源：

PROSTATE CANCER AND PROSTATIC DISEASES | 2000年 / 3卷 / 02期

关键词：

prostate cancer; prostate; metastasis; neoplasia; metastasis suppressor genes; prognostic markers;

D O I：

10.1038/sj.pcan.4500408

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Current diagnostic methods in prostate cancer are lacking in their ability to predict individual patient outcome which highlights the need for more sensitive prognostic markers. Biological markers are seen as attractive and relevant candidates in current efforts to improve prognostic methods. Since metastasis is the most important component of cancer progression and mortality, markers which are able to predict the likely acquisition of the metastatic phenotype, before the onset of metastases, would be extremely useful clinically. This review outlines various metastasis suppressor genes and metastasis promoters which might have potential prognostic use in prostate cancer.

引用

页码：62 / 65

页数：4

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