Arsenic burden among children in industrial areas of eastern Germany

被引:30
作者
Trepka, MJ [1 ]
Heinrich, J [1 ]
Schulz, C [1 ]
Krause, C [1 ]
Popescu, M [1 ]
Wjst, M [1 ]
Wichmann, HE [1 ]
机构
[1] FED ENVIRONM AGCY,INST WATER SOIL & AIR HYG,D-14191 BERLIN,GERMANY
关键词
arsenic; biomonitoring; epidemiology; children;
D O I
10.1016/0048-9697(95)04945-2
中图分类号
X [环境科学、安全科学];
学科分类号
08 ; 0830 ;
摘要
The internal burden of arsenic among 5- to 14-year-old eastern German children in the heavily polluted areas of Hettstedt, a region of smelting and copper mining, and Bitterfeld, a center of chemical production and coal mining, was compared with that in a control area (Zerbst) by means of urinary arsenic concentrations in 1992-94. The unadjusted geometric mean among the 950 children was significantly higher in Hettstedt (5.1 mu g/l; 95% C.I. 4.8-5.5) but not in Bitterfeld (4.3 mu g/l; 95% C.I. 3.7-4.9) compared with the control area (4.0 mu g/l; 95% C.I. 3.5-4.5). This difference persisted after adjustment for relevant confounders. Despite these regional differences, recent fish consumption was as strongly associated with urinary arsenic levels (42% increase, 95% C.I. 18-71%). Additionally, although the geometric mean among the children in Hettstedt (4.8 mu g As/g creatinine; 95% C.I. 4.5-5.1) was higher than that found in an environmental survey of eastern German children (3.60 mu g As/g creatinine; 95% C.I. 3.06-4.24), it was similar to that found among western German children (4.59 mu g As/g creatinine; 95% C.I. 4.20-5.02), This suggests that the arsenic contamination in Hettstedt is not substantially increasing the internal burden of arsenic among children above that found in other German children.
引用
收藏
页码:95 / 105
页数:11
相关论文
共 22 条
[1]   ENVIRONMENTAL EXPOSURE TO LEAD AND ARSENIC AMONG CHILDREN LIVING NEAR A GLASSWORKS [J].
ANDREN, P ;
SCHUTZ, A ;
VAHTER, M ;
ATTEWELL, R ;
JOHANSSON, L ;
WILLERS, S ;
SKERFVING, S .
SCIENCE OF THE TOTAL ENVIRONMENT, 1988, 77 (01) :25-34
[2]  
*ARB TUV BAY LUB L, 1991, ABSCHL FORSCH ENTW U
[3]   NATIONWIDE SURVEY OF HEAVY-METAL ABSORPTION IN CHILDREN LIVING NEAR PRIMARY COPPER, LEAD, AND ZINC SMELTERS [J].
BAKER, EL ;
HAYES, CG ;
LANDRIGAN, PJ ;
HANDKE, JL ;
LEGER, RT ;
HOUSWORTH, WJ ;
HARRINGTON, JM .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 1977, 106 (04) :261-273
[4]   ARSENIC INGESTION AND INTERNAL CANCERS - A REVIEW [J].
BATES, MN ;
SMITH, AH ;
HOPENHAYNRICH, C .
AMERICAN JOURNAL OF EPIDEMIOLOGY, 1992, 135 (05) :462-476
[5]  
BECHER H, 1992, HDB UMWELTMEDIZIN, P1
[6]   TEST OF ENVIRONMENTAL EXPOSURE TO ARSENIC AND HEARING CHANGES IN EXPOSED CHILDREN [J].
BENCKO, V ;
SYMON, K .
ENVIRONMENTAL HEALTH PERSPECTIVES, 1977, 19 (AUG) :95-101
[7]   REPEATED SURVEILLANCE OF EXPOSURE TO CADMIUM, MANGANESE, AND ARSENIC IN SCHOOL-AGE CHILDREN LIVING IN RURAL, URBAN, AND NON-FERROUS SMELTER AREAS IN BELGIUM [J].
BUCHET, JP ;
ROELS, H ;
LAUWERYS, R ;
BRUAUX, P ;
CLAEYSTHOREAU, F ;
LAFONTAINE, A ;
VERDUYN, G .
ENVIRONMENTAL RESEARCH, 1980, 22 (01) :95-108
[8]   ARSENIC AND CADMIUM EXPOSURE IN CHILDREN LIVING NEAR A SMELTER COMPLEX IN SAN-LUIS-POTOSI, MEXICO [J].
DIAZBARRIGA, F ;
SANTOS, MA ;
MEJIA, JD ;
BATRES, L ;
YANEZ, L ;
CARRIZALES, L ;
VERA, E ;
DELRAZO, LM ;
CEBRIAN, ME .
ENVIRONMENTAL RESEARCH, 1993, 62 (02) :242-250
[9]  
EWERS U, 1993, HDB UMWELTMEDIZIN, P1
[10]   HEAVY-METAL EXPOSURE IN POPULATIONS LIVING AROUND ZINC AND COPPER SMELTERS [J].
HARTWELL, TD ;
HANDY, RW ;
HARRIS, BS ;
WILLIAMS, SR ;
GEHLBACH, SH .
ARCHIVES OF ENVIRONMENTAL HEALTH, 1983, 38 (05) :284-295