Synthesis of a new C-2-symmetric molecule with dimeric hydroxyethylene isosteric moiety

被引:10
作者
Chakraborty, TK
Dutta, S
机构
[1] Indian Inst. of Chemical Technology
关键词
D O I
10.1080/00397919708005464
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
As part of our studies directed toward the development of new HIV protease inhibitors, a new type of C-2-symmetric molecule having a dimeric hydroxyethylene isosteric moiety is synthesised by Cu(II)-mediated dimerisation of the sodium enolate of an amino acid-derived methylketo copound.
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页码:4163 / 4172
页数:10
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