Surface functionalization of amorphous silicon and silicon suboxides for biological applications

被引：25

作者：

Dahmen, C

Janotta, A

Dimova-Malinovska, D

Marx, S

Jeschke, B

Nies, B

Kessler, H

Stutzmann, M

机构：

[1] Tech Univ Munich, Walter Schottky Inst, D-85748 Garching, Germany

[2] Tech Univ Munich, Inst Organ Chem & Biochem 2, D-85748 Garching, Germany

[3] Bulgarian Acad Sci, Cent Lab Solar Energy & New Energy Resources, Sofia 1784, Bulgaria

[4] Tech Univ Munich, Phys Dept E22, D-85748 Garching, Germany

[5] Merck Biomat GmbH, D-64271 Darmstadt, Germany

来源：

THIN SOLID FILMS | 2003年 / 427卷 / 1-2期

关键词：

amorphous silicon; silicon suboxides; surface functionalization; hydrosilylation; cell adhesion; RGD peptides;

D O I：

10.1016/S0040-6090(02)01228-2

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

We have studied the chemical modification and functionalization of the surface of hydrogenated amorphous silicon (a-Si:H) and silicon suboxides (a-SiOx:H) for the purpose of selective cell adhesion. The preparation of hydrophobic /hydrophilic contrast on the amorphous surfaces has been investigated systematically as a function of the oxygen content by contact angle measurements. Successful functionalization of a-Si:H by hydrosilylation with methyl acrylate is reported and analyzed by thermal desorption studies as well as enzyme linked immunosorbent assays using RGD-peptide derivatives. (C) 2002 Elsevier Science B.V. All rights reserved.

引用

页码：201 / 207

页数：7

共 16 条

[1] Spectroscopic studies of the modification of crystalline Si(111) surfaces with covalently-attached alkyl chains using a chlorination/alkylation method [J].