Prenatal diagnosis of trisomy 18 at the 10-14 week ultrasound scan

被引：71

作者：

Sherod, C ^{[1
]}

Sebire, NJ ^{[1
]}

Soares, W ^{[1
]}

Snijders, RJM ^{[1
]}

Nicolaides, KH ^{[1
]}

机构：

[1] Univ London Kings Coll Hosp, Sch Med, Harris Birthright Res Ctr Fetal Med, London SE5 8RX, England

来源：

ULTRASOUND IN OBSTETRICS & GYNECOLOGY | 1997年 / 10卷 / 06期

关键词：

trisomy; 18; first trimester; prenatal diagnosis; ultrasound;

D O I：

10.1046/j.1469-0705.1997.10060387.x

中图分类号：

O42 [声学];

学科分类号：

070206 ; 082403 ;

摘要：

A beneficial consequence of screening for trisomy 21 by a combination of maternal age and fetal nuchal translucency thickness (NT) at 10-14 weeks is the early diagnosis of trisomy 18. In a multicenter study of 91 091 singleton pregnancies there were 106 fetuses with trisomy 18 and 83% were identified by NT screening. Trisomy 18 was also associated with early onset intrauterine growth retardation, decreased fetal heart rate and the presence of exomphalos.

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页码：387 / 390

页数：4

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