Rate enhancement of the Morita-Baylis-Hillman reaction through mechanochemistry

被引：96

作者：

Mack, James ^{[1
]}

Shumba, Maxwell ^{[1
]}

机构：

[1] Univ Cincinnati, Cincinnati, OH 45221 USA

来源：

GREEN CHEMISTRY | 2007年 / 9卷 / 04期

关键词：

D O I：

10.1039/b612983h

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Through the novel technique of high speed ball milling we were able to generate Baylis - Hillman products in as little as 0.5 hours. This represents one of the fastest methods of Baylis - Hillman reactions under neat conditions. Upon analysis of various catalysts we found 1,4-diazabicyclo[ 2.2.2] octane to be the catalyst that led to the highest product yields in the shortest reaction time.

引用

收藏

页码：328 / 330

页数：3

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