A communication means for totally locked-in ALS patients based on changes in cerebral blood volume measured with near-infrared light

被引：151

作者：

Naito, Masayoshi ^{[1
]}

Michioka, Yohko

Ozawa, Kuniaki

Ito, Yoshitoshi

Kiguchi, Masashi

Kanazawa, Tsuneo

机构：

[1] Tokyo Womans Christian Univ, Coll Arts & Sci, Dept Math, Tokyo 1678585, Japan

[2] Kagoshima Univ, Grad Sch Sci & Engn, Dept Bioengn, Kagoshima 8900065, Japan

[3] Ubiquitous Syst Div, Tokyo 1000004, Japan

[4] Hitachi Ltd, Cent Res Lab, Kokubunji, Tokyo 1858601, Japan

[5] Execl Mechatronix Co Ltd, Tokyo 1770052, Japan

[6] Tokyo Womans Christian Univ, Coll Arts & Sci, Dept Math, Tokyo 1678585, Japan

[7] Grad Sch Sci & Engn, Dept Bioengn, Kagoshima 8900065, Japan

[8] Ubiquitous Syst Div, Tokyo 1000004, Japan

[9] Excel Mechatronix Co Ltd, Tokyo 1770052, Japan

来源：

IEICE TRANSACTIONS ON INFORMATION AND SYSTEMS | 2007年 / E90D卷 / 07期

关键词：

amyotrophic lateral sclerosis; human communication; near infrared light; discriminant analysis; brain-computer interface;

D O I：

10.1093/ietisy/e90-d.7.1028

中图分类号：

TP [自动化技术、计算机技术];

学科分类号：

0812 ;

摘要：

A communication means is presented for patients with amyotrophic lateral sclerosis in totally locked-in state who are completely unable to move any part of the body and have no usual communication means. The method utilizes changes in cerebral blood volume accompanied with changes in brain activity. When a patient is asked a question and the answer to it is 'yes', the patient makes his or her brain active. The change in blood volume at the frontal lobe is detected with near-infrared light. The instantaneous amplitude and phase of the change are calculated, and the maximum amplitude and phase change are obtained. The answer 'yes' or 'no' of the patient is detected using a discriminant analysis with these two quantities as variables. The rate of correct detection is 80% on average.

引用

页码：1028 / 1037

页数：10

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