Coronary stenting in stable patients: Identification of a low-risk subgroup that may not require adjunctive antiplatelet therapy

被引：5

作者：

Mann, T ^{[1
]}

Cubeddu, RJ ^{[1
]}

Raynor, L ^{[1
]}

Bowen, J ^{[1
]}

Schneider, JE ^{[1
]}

Rose, G ^{[1
]}

Cubeddu, G ^{[1
]}

Raza, JA ^{[1
]}

Jobe, RL ^{[1
]}

Newman, W ^{[1
]}

Zellinger, M ^{[1
]}

机构：

[1] Wake Heart Ctr, Raleigh, NC USA

来源：

CATHETERIZATION AND CARDIOVASCULAR INTERVENTIONS | 2003年 / 58卷 / 04期

关键词：

coronary intervention; abciximab; coronary artery disease;

D O I：

10.1002/ccd.10479

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The present study prospectively evaluated adjunctive antiplatelet therapy in patients without insulin-requiring diabetes during elective coronary stenting. Three hundred patients were randomized to one of three treatment groups: clopidogrel pretreatment, adjunctive abciximab, or control. Stenting was successful in 98% and no deaths occurred. Thirty-day and 1-year major adverse coronary events (MACEs) was similar in all groups. A subgroup of 109 patients undergoing single-vessel stenting of type A/B1 lesions with short guidewire times had no postprocedure myocardial infarction or 30-day MACE. We conclude that patients with these characteristics may safely undergo elective coronary stenting without adjunctive antiplatelet therapy.

引用

页码：459 / 466

页数：8

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