High prevalence of calcified silent neurocysticercosis in a rural village of Mexico

被引：111

作者：

Fleury, A

Gomez, T

Alvarez, I

Meza, D

Huerta, M

Chavarria, A

Mezo, RAC

Lloyd, C

Dessein, A

Preux, PM

Dumas, M

Larralde, C

Sciutto, E

Fragoso, G

机构：

[1] Univ Nacl Autonoma Mexico, Inst Invest Biomed, Mexico City 04510, DF, Mexico

[2] Inst Nacl Neurol & Neurocirugia Manuel Velazco Su, Mexico City, DF, Mexico

[3] INSERM, F-13258 Marseille, France

[4] Inst Epidemiol Neurol & Neurol Trop, Limoges, France

[5] BUAP, Puebla, Mexico

[6] Hosp Gen Puebla, Puebla, Mexico

来源：

NEUROEPIDEMIOLOGY | 2003年 / 22卷 / 02期

关键词：

neurocysticercosis; epidemiology; CT scan; Taenia solium; cysticercosis;

D O I：

10.1159/000068748

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Human neurocysticercosis (NC) is a parasitic disease caused by Taenia solium when its larvae lodge in the central nervous system. NC prevalence estimates are obscured by the variable and often asymptomatic clinical picture. While infection depends on exposure, severity is possibly related with various host factors (immunity, genes and gender). This epidemiological study of cranial CT scans in an endemic rural community found that 9.1% of apparently healthy subjects had calcified lesions and were completely asymptomatic. Silent NC cases did not correlate with the exposure factors tested but showed family aggregation and higher rates of positive serology. Thus, NC prevalence may be higher than currently considered and host-related factors appear to be involved in infection and pathogenesis. Copyright (C) 2003 S. Karger AG, Basel.

引用

页码：139 / 145

页数：7

共 31 条

[1] The impact of host genetics on susceptibility to human infectious diseases [J].