The use of topiramate in refractory status epilepticus

被引：116

作者：

Towne, AR ^{[1
]}

Garnett, LK ^{[1
]}

Waterhouse, EJ ^{[1
]}

Morton, LD ^{[1
]}

DeLorenzo, RJ ^{[1
]}

机构：

[1] Virginia Commonwealth Univ Hlth Syst, Dept Neurol, Richmond, VA 23298 USA

来源：

NEUROLOGY | 2003年 / 60卷 / 02期

关键词：

D O I：

10.1212/01.WNL.0000042783.86439.27

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

In cases of refractory status epilepticus (RSE) unresponsive to sequential trials of multiple agents, a suspension of topiramate administered via nasogastric tube was effective in aborting RSE, including one patient in a prolonged pentobarbital coma. Effective dosages ranged from 300 to 1,600 mg/d. Except for lethargy, no adverse events were reported.

引用

页码：332 / 334

页数：3

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