Effect of estrogen on cerebral glucose metabolism in postmenopausal women

被引：52

作者：

Eberling, JL

Reed, BR

Coleman, JE

Jagust, WJ

机构：

[1] Univ Calif Berkeley, Lawrence Berkeley Lab, Ctr Funct Imaging, Berkeley, CA 94720 USA

[2] Univ Calif Davis, Dept Neurol, Davis, CA 95616 USA

[3] Univ Calif Davis, Alzheimers Dis Ctr, Davis, CA 95616 USA

来源：

NEUROLOGY | 2000年 / 55卷 / 06期

关键词：

D O I：

10.1212/WNL.55.6.875

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

PET was used to evaluate the effect of estrogen use on regional cerebral glucose metabolism in postmenopausal women. Women receiving estrogen replacement therapy (ERT+), women not receiving estrogen (ERT-), and women with AD were studied. The ERT- group showed metabolic ratios that were intermediate to the ERT+ and AD groups, although they did not show any signs of cognitive impairment. These findings show an effect of estrogen depletion on brain metabolic activity.

引用

收藏

页码：875 / 877

页数：3

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