Gastrin, growth, and colon neoplasia

被引：16

作者：

Dockray, GJ ^{[1
]}

机构：

[1] Univ Liverpool, Physiol Lab, Liverpool L69 3BX, Merseyside, England

来源：

GUT | 2000年 / 47卷 / 06期

关键词：

D O I：

10.1136/gut.47.6.747

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

引用

页码：747 / 748

页数：2

共 11 条

[1] Glycine-extended gastrin acts as an autocrine growth factor in a nontransformed colon cell line [J].

Hollande, F ;

Imdahl, A ;

Mantamadiotis, T ;

Ciccotosto, GD ;

Shulkes, A ;

Baldwin, GS .

GASTROENTEROLOGY, 1997, 113 (05) :1576-1588

[2] REGULATION OF GASTROINTESTINAL MUCOSAL GROWTH [J].

JOHNSON, LR .

PHYSIOLOGICAL REVIEWS, 1988, 68 (02) :456-502

[3] Gastrin is a target of the β-catenin/TCF-4 growth-signaling pathway in a model of intestinal polyposis [J].

Koh, TJ ;

Bulitta, CJ ;

Fleming, JV ;

Dockray, GJ ;

Varro, A ;

Wang, TC .

JOURNAL OF CLINICAL INVESTIGATION, 2000, 106 (04) :533-539

[4] Overexpression of glycine-extended gastrin in transgenic mice results in increased colonic proliferation [J].

Koh, TJ ;

Dockray, GJ ;

Varro, A ;

Cahill, RJ ;

Dangler, CA ;

Fox, JG ;

Wang, TC .

JOURNAL OF CLINICAL INVESTIGATION, 1999, 103 (08) :1119-1126

[5] Oncogenic ras induces gastrin gene expression in colon cancer [J].

Nakata, H ;

Wang, SL ;

Chung, DC ;

Westwick, JK ;

Tillotson, LG .

GASTROENTEROLOGY, 1998, 115 (05) :1144-1153

[6] Progastrin expression predisposes mice to colon carcinomas and adenomas in response to a chemical carcinogen [J].

Singh, P ;

Velasco, M ;

Given, R ;

Varro, A ;

Wang, TC .

GASTROENTEROLOGY, 2000, 119 (01) :162-171

[7] Mice overexpressing progastrin are predisposed for developing aberrant colonic crypt foci in response to AOM [J].

Singh, P ;

Velasco, M ;

Given, R ;

Wargovich, M ;

Varro, A ;

Wang, TC .

AMERICAN JOURNAL OF PHYSIOLOGY-GASTROINTESTINAL AND LIVER PHYSIOLOGY, 2000, 278 (03) :G390-G399

[8] Gastrin and gastrin receptor activation: an early event in the adenoma-carcinoma sequence [J].

Smith, AM ;

Watson, SA .

GUT, 2000, 47 (06) :820-824

[9]

VARRO A, 1994, J BIOL CHEM, V269, P20764

[10] Processing and proliferative effects of human progastrin in transgenic mice [J].

Wang, TC ;

Koh, TJ ;

Varro, A ;

Cahill, RJ ;

Dangler, CA ;

Fox, JG ;

Dockray, GJ .

JOURNAL OF CLINICAL INVESTIGATION, 1996, 98 (08) :1918-1929

← 1 2 →