MouseNet© database:: digital management of a large-scale mutagenesis project

被引：14

作者：

Pargent, W ^{[1
]}

Heffner, S ^{[1
]}

Schäble, KF ^{[1
]}

Soewarto, D ^{[1
]}

Fuchs, H ^{[1
]}

de Angelis, MH ^{[1
]}

机构：

[1] GSF, Res Ctr Environm & Hlth, Inst Expt Genet, D-85764 Neuherberg, Germany

来源：

MAMMALIAN GENOME | 2000年 / 11卷 / 07期

关键词：

D O I：

10.1007/s003350010112

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The Munich ENU Mouse Mutagenesis Screen is a large-scale mutant production, phenotyping, and mapping project. It encompasses two animal breeding facilities and a number of screening groups located in the general area of Munich. A central database is required to manage and process the immense amount of data generated by the mutagenesis project. This database, which we named MouseNet(C), runs on a Sybase platform and will finally store and process all data from the entire project. In addition, the system comprises a portfolio of functions needed to support the workflow management of the core facility and the screening groups. MouseNet(C) will make all of the data available to the participating screening groups, and later to the international scientific community. MouseNet(C) will consist of three major software components: Animal Management System (AMS) Sample Tracking System (STS) Result Documentation System (RDS) MouseNet(C) provides the following major advantages: being accessible from different client platforms via the Internet being a full-featured multi-user system (including access restriction and data locking mechanisms) relying on a professional RDBMS (relational database management system) which runs on a UNIX server platform supplying workflow functions and a variety of plausibility checks.

引用

页码：590 / 593

页数：4