Oxytocin during pregnancy and early postpartum: Individual patterns and maternal-fetal attachment

被引:208
作者
Levine, Ari
Zagoory-Sharon, Orna
Feldman, Ruth
Weller, Aron [1 ]
机构
[1] Bar Ilan Univ, Interdisciplinary Program Brain Sci, IL-52900 Ramat Gan, Israel
[2] Bar Ilan Univ, Gonda Goldschmeid Brain Res Ctr, IL-52900 Ramat Gan, Israel
[3] Bar Ilan Univ, Dept Psychol, IL-52900 Ramat Gan, Israel
基金
以色列科学基金会; 美国国家科学基金会;
关键词
oxytocin; longitudinal; pregnancy; perinatal; enzyme immuno-assay (EIA); maternal-fetal attachment scale;
D O I
10.1016/j.peptides.2007.04.016
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
Oxytocin (OT), a nanopeptide hormone, plays a role in the emergence of maternal behavior, yet few studies examined OT in humans across pregnancy and the postpartum. We followed healthy women at three points: first trimester of pregnancy, third trimester, and first postpartum month. Plasma OT levels showed high individual stability. A third of the sample showed consistent OT levels, whereas others showed increasing or decreasing trends or peak in late pregnancy. The increase in OT from early to late pregnancy correlated with higher maternal-fetal bonding. These data may help set standards for OT levels and underscore links with maternal-infant attachment. (c) 2007 Elsevier Inc. All rights reserved.
引用
收藏
页码:1162 / 1169
页数:8
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