The ion gating effect: using a change in flexibility to allow label free electrochemical detection of DNA hybridisation

被引：56

作者：

Gooding, JJ ^{[1
]}

Chou, A ^{[1
]}

Mearns, FJ ^{[1
]}

Wong, E ^{[1
]}

Jericho, KL ^{[1
]}

机构：

[1] Univ New S Wales, Sch Chem Sci, Sydney, NSW 2052, Australia

来源：

CHEMICAL COMMUNICATIONS | 2003年 / 15期

关键词：

D O I：

10.1039/b305798b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A label free electrochemical method of detecting DNA hybridisation is presented based on the change in flexibility between a single strand of DNA and a duplex causing an ion-gating effect where hybridisation opens up the electrode to access of ions.

引用

页码：1938 / 1939

页数：2

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