The sodium "leak" has finally been plugged

被引:20
作者
Snutch, Terrance P. [1 ]
Monteil, Arnaud
机构
[1] Univ British Columbia, Michael Smith Labs, Vancouver, BC V6T 1Z4, Canada
[2] Univ Montpellier I, CNRS, UMR5203, INSERM,U661,Dept Physiol,Inst Genom Fonct, F-34094 Montpellier 5, France
[3] Univ Montpellier 2, CNRS, UMR5203, INSERM,U661,Dept Physiol,Inst Genom Fonct, F-34094 Montpellier 5, France
关键词
D O I
10.1016/j.neuron.2007.05.005
中图分类号
Q189 [神经科学];
学科分类号
071006 ;
摘要
Most electrophysiologists generally do not speak highly of leak currents. In reality, these conductances represent a crucial functional mechanism by which neurons control resting membrane potentials. A new study in Cell by Lu et al. has surprisingly confirmed the identity of the long-sought voltage-insensitive sodium leak conductance to be encoded by the third branch of the voltage-gated sodium and calcium channel family.
引用
收藏
页码:505 / 507
页数:3
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