Effect of radiation on prothrombin interactions with cell membrane fragments

被引：1

作者：

Kiselev, SV ^{[1
]}

Zubairov, DM ^{[1
]}

Kirshin, SV ^{[1
]}

机构：

[1] Kazan State Med Univ, Kazan, Russia

来源：

BULLETIN OF EXPERIMENTAL BIOLOGY AND MEDICINE | 2002年 / 134卷 / 05期

关键词：

prothrombin; cell membrane fragments; radiation exposure;

D O I：

10.1023/A:1022630011907

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 [基础医学];

摘要：

Binding of I-125-labeled prothrombin to normal and radiation-damaged (1 and 3.5 Gy) fragments of cell membranes was studied. Irradiation significantly increased adsorption capacity of cell membranes for I-125-prothrombin. It was concluded that phase rearrangement of phospholipids serves as the molecular basis for increased thrombogenicity of cell membranes.

引用

页码：442 / 444

页数：3

共 14 条

[1]

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[2]

GERADS I, 1990, BIOCHEMISTRY-US, V29, P20288

[3]

PREPARATION OF IODINE-131 LABELLED HUMAN GROWTH HORMONE OF HIGH SPECIFIC ACTIVITY [J].