Neural pathogenesis of enterovirus 71 infection

被引:178
作者
Weng, Kuo-Feng [1 ,2 ]
Chen, Li-Lien [1 ,3 ]
Huang, Peng-Nien [1 ,2 ]
Shih, Shin-Ru [1 ,2 ]
机构
[1] Chang Gung Univ, Res Ctr Emerging Viral Infect, Tao Yuan 333, Taiwan
[2] Chang Gung Univ, Dept Med Biotechnol & Lab Sci, Tao Yuan 333, Taiwan
[3] Chang Gung Univ, Grad Inst Biomed Sci, Tao Yuan 333, Taiwan
关键词
Enterovirus; 71; EV71; Picornaviridae; Picornavirus; Neuron; Neural; Pathogenesis; CENTRAL-NERVOUS-SYSTEM; BRAIN-STEM ENCEPHALITIS; POLIOMYELITIS-LIKE DISEASE; MR-IMAGING FINDINGS; CEREBROSPINAL-FLUID; VIRAL ENCEPHALITIS; TYPE-71; INFECTIONS; PULMONARY-EDEMA; WHITE-MATTER; VIRUS;
D O I
10.1016/j.micinf.2010.03.006
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
Enterovirus 71 (EV71) is a neurotropic pathogen that can cause severe neural diseases and complications on infected patients. Clinical observations showed that EV71-induced immune responses may be associated with virus induced neurogenic pulmonary edema. Here reviewed studies that discovered several host molecules as potential factors for EV71 virulence. (C) 2010 Elsevier Masson SAS. All rights reserved.
引用
收藏
页码:505 / 510
页数:6
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