Hepatoblastoma associated with Beckwith-Wiedemann syndrome and hemihypertrophy

被引：23

作者：

Hamada, Y ^{[1
]}

Takada, K ^{[1
]}

Fukunaga, S ^{[1
]}

Hioki, K ^{[1
]}

机构：

[1] Kansai Med Univ, Dept Surg 2, Moriguchi, Osaka 5708507, Japan

来源：

PEDIATRIC SURGERY INTERNATIONAL | 2003年 / 19卷 / 1-2期

关键词：

hepatoblastoma; Beckwith-Wiedemann syndrome; hemihypertrophy; alpha-fetoprotein;

D O I：

10.1007/s00383-002-0734-2

中图分类号：

R72 [儿科学];

学科分类号：

100202 ;

摘要：

Both Beckwith-Wiedemann syndrome (BWS) and hemihypertrophy (HH) have been recognized to be overgrowth syndromes associated with an increased risk of cancer. We report an infant with hepatoblastoma associated with both BWS and HH in whom high serum alpha-fetoprotein (AFP) levels persisted even after complete tumor resection with no tumor recurrence. This phenomenon might be partly due to the nature of the proliferative disease. It is important to recognize that in some infants with BWS prolonged high serum AFP levels mimic the existence of a tumor, and that treatment should be based not only on AFP measurement, but also on repeated radiologic imaging.

引用

页码：112 / 114

页数：3

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