New total synthesis of (±)-herbertene, (±)-β-herbertenol and (±)-herbertenediol

被引：23

作者：

Gupta, PD ^{[1
]}

Pal, A ^{[1
]}

Roy, A ^{[1
]}

Mukherjee, D ^{[1
]}

机构：

[1] Indian Assoc Cultivat Sci, Dept Organ Chem, Calcutta 700032, W Bengal, India

来源：

TETRAHEDRON LETTERS | 2000年 / 41卷 / 39期

关键词：

terpenes; phenols; Grignard reagents; alkylation; cyclopentanones;

D O I：

10.1016/S0040-4039(00)01298-3

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The total syntheses of the herbertane sesquiterpenes (+/-)-herbertene (1): (+/-)-beta-herbertenol (2) and (+/-)-herbertenediol (5) have been successfully accomplished involving copper-catalysed conjugate addition of Grignard reagents to unsaturated compounds and alpha,alpha-dimethylation of primary esters as key reactions. (C) 2000 Elsevier Science Ltd. All rights reserved.

引用

页码：7563 / 7566

页数：4

共 7 条

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