NF-κB signaling proteins as therapeutic targets for inflammatory bowel diseases

被引：108

作者：

Jobin, C

Sartor, RB

机构：

[1] Univ N Carolina, Dept Med, Chapel Hill, NC 27599 USA

[2] Univ N Carolina, Dept Microbiol & Immunol, Chapel Hill, NC 27599 USA

[3] Univ N Carolina, Ctr Gastrointestinal Biol & Dis, Chapel Hill, NC 27599 USA

来源：

INFLAMMATORY BOWEL DISEASES | 2000年 / 6卷 / 03期

关键词：

D O I：

10.1097/00054725-200008000-00007

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

[No abstract available]

引用

页码：206 / 213

页数：8

共 74 条

[1] Targeted disruption of the MyD88 gene results in loss of IL-1- and IL-18-mediated function [J].

Adachi, O ;

Kawai, T ;

Takeda, K ;

Matsumoto, M ;

Tsutsui, H ;

Sakagami, M ;

Nakanishi, K ;

Akira, S .

IMMUNITY, 1998, 9 (01) :143-150

[2]

BAEUERLE PA, 1994, ANNU REV IMMUNOL, V12, P141, DOI 10.1146/annurev.immunol.12.1.141

[3] Mechanisms of disease - Nuclear factor-kappa b - A pivotal transcription factor in chronic inflammatory diseases [J].

Barnes, PJ ;

Larin, M .

NEW ENGLAND JOURNAL OF MEDICINE, 1997, 336 (15) :1066-1071

[4] Cellular differentiation causes a selective down-regulation of interleukin (IL)-1β-mediated NF-κB activation and IL-8 gene expression in intestinal epithelial cells [J].

Böcker, U ;

Schottelius, A ;

Watson, JM ;

Holt, L ;

Licato, LL ;

Brenner, DA ;

Sartor, RB ;

Jobin, C .

JOURNAL OF BIOLOGICAL CHEMISTRY, 2000, 275 (16) :12207-12213

[5] CENTRAL OF I-KAPPA-B-ALPHA PROTEOLYSIS BY SITE-SPECIFIC, SIGNAL-INDUCED PHOSPHORYLATION [J].

BROWN, K ;

GERSTBERGER, S ;

CARLSON, L ;

FRANZOSO, G ;

SIEBENLIST, U .

SCIENCE, 1995, 267 (5203) :1485-1488

[6] MyD88, an adapter protein involved in interleukin-1 signaling [J].

Burns, K ;

Martinon, F ;

Esslinger, C ;

Pahl, H ;

Schneider, P ;

Bodmer, JL ;

Di Marco, F ;

French, L ;

Tschopp, J .

JOURNAL OF BIOLOGICAL CHEMISTRY, 1998, 273 (20) :12203-12209

[7] TARF6 is a signal transducer for interleukin-1 [J].

Cao, ZD ;

Xiong, J ;

Takeuchi, M ;

Kurama, T ;

Goeddel, DV .

NATURE, 1996, 383 (6599) :443-446

[8] IRAK: A kinase associated with the interleukin-1 receptor [J].

Cao, ZD ;

Henzel, WJ ;

Gao, XO .

SCIENCE, 1996, 271 (5252) :1128-1131

[9]

Chen F, 1999, CLIN CHEM, V45, P7

[10] Regulation of DNA binding by Rel/NF-κB transcription factors:: structural views [J].

Chen, FE ;

Ghosh, G .

ONCOGENE, 1999, 18 (49) :6845-6852

← 1 2 3 4 5 6 7 8 →